https://www.healingthroughgenes.com/podcast daily 0.75 2026-03-28 https://www.healingthroughgenes.com/podcast/episode-6-rewriting-the-blueprint-how-crispr-offers-new-hope-for-anxiety monthly 0.5 2025-01-12 https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/12357f76-681c-4dcd-91fe-5981ebcca584/Picture1.png PODCAST - Episode #6 - Rewriting the Blueprint: How CRISPR Offers New Hope for Anxiety The CRISPR system has two key components that work together for gene editing. The guide RNA acts like a set of GPS coordinates, directing the Cas9 protein to the precise location in the DNA that needs to be altered. Once at the target, the Cas9 protein functions as molecular scissors, cutting both DNA strands of the helix to enable the desired changes. https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/adfcb996-fe73-4bb3-8193-30d54d40a842/Picture2.png PODCAST - Episode #6 - Rewriting the Blueprint: How CRISPR Offers New Hope for Anxiety - Illustration depicts two methods by which cells can mend double-stranded breaks (DSBs), following cleavage by CRISPR/Cas9. On the left is Non-homologous end joining (NHEJ), a faster but less accurate technique than HDR. It links the damaged DNA ends without requiring a template, often resulting in unintentional insertions or deletions. NHEJ is the repair system that neurons rely on. The right side depicts Homology Directed Repair (HDR), which utilizes a complementary piece of DNA (donor DNA) to mend the break precisely. However, the cellular machinery for this is only present in dividing cells. https://www.healingthroughgenes.com/podcast/episode-5-the-serotonin-solution-targeting-the-5-ht2a-receptor-to-rewire-anxiety monthly 0.5 2024-12-28 https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/f96ea03d-c4e9-40ba-aee0-be9f607d6a4c/podcast5-Picture1.png PODCAST - Episode #5 - The Serotonin Solution: Targeting the 5-HT2A Receptor to Rewire Anxiety - The “hyperactive distressive connectome” hypothesis, as illustrated, involves key brain hubs, including the insula, hippocampus, amygdala, and thalamus. When hyperactivity is present in this network, it can perpetuate a cycle off emotional distress, leading to chronic anxiety. https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/16cdd4a2-b073-4225-8e64-c4a8d6ef9dee/podcast5-Picture2.png PODCAST - Episode #5 - The Serotonin Solution: Targeting the 5-HT2A Receptor to Rewire Anxiety - The serotonin synapse. The synapse is a narrow gap between the presynaptic and postsynaptic terminals of adjacent neurons at a synapse. It serves as a physical barrier for transmitting electrical signals between neurons. Neurotransmitters are chemicals that bridge that gap and allow the electrical signal to be converted into a chemical signal. In this case, serotonin is released by the presynaptic neuron into the synapse, diffusing across the gap to bind with, in this example, 5 - HT2A receptors on the postsynaptic neuron, thereby facilitating the transfer of information between neurons. The result is an increased excitability (firing rate) of the postsynaptic neuron. https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/4c68a132-698c-4eca-a3a5-dd3e2a43d754/podcast5-Picture3.png PODCAST - Episode #5 - The Serotonin Solution: Targeting the 5-HT2A Receptor to Rewire Anxiety My tattoo depicts the molecular structure of serotonin, a key neurotransmitter involved in mood regulation, alongside the 5-HT2A receptor gene (HTR2A), which plays a critical role i serotonin signaling. The tattoo symbolizes my own personal and professional investment in the serotonin pathway. https://www.healingthroughgenes.com/podcast/episode-4-from-code-to-cure-how-dna-writes-the-protein-blueprint monthly 0.5 2024-12-04 https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/78e775b1-e8a6-4a3c-a426-b9929e2a9495/Screenshot+2024-12-03+120337.png PODCAST - Episode #4 - From Code to Cure: How DNA Writes the Protein Blueprint This schematic illustrates the process of using DNA to create proteins. First, the information in DNA is copied into mRNA during a process called transcription. The next step is translation, whereby the mRNA is read in groups of three nucleotides known as codons to form a protein. Each codon represents an amino acid. https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/d26a2e34-8f93-4b74-8fe1-55da5d2fbd18/Screenshot+2024-12-04+at+1.50.37%E2%80%AFPM.png PODCAST - Episode #4 - From Code to Cure: How DNA Writes the Protein Blueprint - Types of Mutations to DNA This figure illustrates how different DNA mutations can affect the mRNA sequence and the resulting protein. The “Normal sequence” in the top-left panel shows an mRNA sequence with no mutations, producing a functional protein. In the top-right panel, a “Base-pair deletion” removes a single nucleotide, causing a frameshift mutation that alters the reading frame and changes the resulting amino acids. The bottom-left panel shows a “Base-pair insertion,” where an extra nucleotide causes an immediate stop codon, leading to a shortened, nonfunctional protein. The bottom-right panel shows a “Three-nucleotide insertion/deletion,” which removes or adds a whole codon, leading to the loss or addition of an amino acid without shifting the reading frame. However, it still affects the protein structure. https://www.healingthroughgenes.com/podcast/episode-3-the-players-in-this-scientific-drama monthly 0.5 2024-12-03 https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/67019732-7603-418f-86bd-b447417704af/Screenshot+2024-11-19+131153.png PODCAST - Episode #3 - The Players in this Scientific Drama https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/092a4e75-1650-463c-b95c-0ba3b3bb3f60/Untitled.png PODCAST - Episode #3 - The Players in this Scientific Drama - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.healingthroughgenes.com/podcast/episode-2-what-me-worry monthly 0.5 2024-12-03 https://www.healingthroughgenes.com/podcast/episode-1-pilot monthly 0.5 2024-12-03 https://www.healingthroughgenes.com/home daily 0.75 2024-11-08 https://www.healingthroughgenes.com/about daily 0.75 2026-03-28 https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/7d4abb59-96c6-427f-b54d-83dc59a21062/4I4A8943.jpeg https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/264cd8f9-105c-49e9-9de2-d7d6596f843b/Preorder+sale+notice%21+%282%29.png https://www.healingthroughgenes.com/transforming-anxiety-with-gene-therapy daily 1.0 2026-03-28 https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/30c698cc-0ba3-4b6e-9917-bef7eeace4d0/Preorder+sale+notice%21+%282%29.png https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/ba49c438-c34b-4296-ae2e-b82e65219a91/madalyn-+lackey-dupe.jpeg https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/697edb33-d9bf-4b20-84a6-3b01818ab85e/caitlin-perry-dupe.jpeg https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/7a7e2774-9e0a-4361-b6b8-bb8e94e5d97e/gabrielly-ernega-dupe.jpeg https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/c52b03b7-b558-4798-9f1b-6d9e52b2d94f/Brain+Medicine.png https://www.healingthroughgenes.com/contact daily 0.75 2026-03-28 https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/a451e2a8-edef-4fa5-95fa-3b7201d82e59/1489.jpg https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/3c69115b-e12b-41c9-a383-a0dac30cedd7/4I4A8943.jpeg https://www.healingthroughgenes.com/reviews-2 daily 0.75 2024-11-04 https://www.healingthroughgenes.com/store daily 0.75 58204-02-23 https://www.healingthroughgenes.com/store/p/brain-medicine monthly 0.5 2026-03-27 https://images.squarespace-cdn.com/content/v1/672932b82adc321a3066fb58/9bb35e08-8507-4a31-b759-86127a3fb7c3/Preorder+sale+notice%21+%281%29.png Store - Brain Medicine - Preorder sale notice! 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